Monday, October 4, 2010

No laps for warm laptops; skin damage is possible.

LINDSEY TANNER
Published: 21 minutes ago
CHICAGO (AP)

Have you ever worked on your laptop computer with it sitting on your lap, heating up your legs? If so, you might want to rethink that habit.

Doing it a lot can lead to "toasted skin syndrome," an unusual-looking mottled skin condition caused by long-term heat exposure, according to medical reports.

In one recent case, a 12-year-old boy developed a sponge-patterned skin discoloration on his left thigh after playing computer games a few hours every day for several months.

"He recognized that the laptop got hot on the left side; however, regardless of that, he did not change its position," Swiss researchers reported in an article published Monday in the journal Pediatrics.

Another case involved a Virginia law student who sought treatment for the mottled discoloration on her leg.

Dr. Kimberley Salkey, who treated the young woman, was stumped until she learned the student spent about six hours a day working with her computer propped on her lap. The temperature underneath registered 125 degrees.

That case, from 2007, is one of 10 laptop-related cases reported in medical journals in the past six years.

The condition also can be caused by overuse of heating pads and other heat sources that usually aren't hot enough to cause burns. It's generally harmless but can cause permanent skin darkening. In very rare cases, it can cause damage leading to skin cancers, said the Swiss researchers, Drs. Andreas Arnold and Peter Itin from University Hospital Basel. They do not cite any skin cancer cases linked to laptop use, but suggest, to be safe, placing a carrying case or other heat shield under the laptop if you have to hold it in your lap.

Salkey, an assistant dermatology professor at Eastern Virginia Medical School, said that under the microscope, the affected skin resembles skin damaged by long-term sun exposure.

Major manufacturers including Apple, Hewlett Packard and Dell warn in user manuals against placing laptops on laps or exposed skin for extended periods of time because of the risk for burns.

A medical report several years ago found that men who used laptops on their laps had elevated scrotum temperatures. If prolonged, that kind of heat can decrease sperm production, which can potentially lead to infertility. Whether laptop use itself can cause that kind of harm hasn't been confirmed.

In the past, "toasted skin syndrome" has occurred in workers whose jobs require being close to a heat source, including bakers and glass blowers, and, before central heating, in people who huddled near potbellied stoves to stay warm.

Dr. Anthony J. Mancini, dermatology chief at Children's Memorial Hospital in Chicago, said he'd treated a boy who developed the condition from using a heating pad "hours at a time" to soothe a thigh injured in soccer. Mancini said he'd also seen a case caused by a hot water bottle.

He noted that chronic, prolonged skin inflammation can potentially increase chances for squamous cell skin cancer, which is more aggressive than the most common skin cancer. But Mancini said it's unlikely computer use would lead to cancer since it's so easy to avoid prolonged close skin contact with laptops.

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Online:

Pediatrics: http://www.pediatrics.org

Thursday, September 2, 2010

A great write up of DERMASPACE & The Iderm Facial Treatment!

Step aside, treadmills and Stairmasters -- there’s a new kind of gym in town, the “Skin-Gym.” With Dermaspace’s Iderm Facial Treatment, or “Skin-Gym,” toning and tightening aren’t just for glutes, triceps and biceps anymore. It’s your face’s turn to get fit. If the typical spa facial is a walk in the park, then the Iderm Facial Treatment, which focuses on deep tissue cleansing, is a one-on-one session with a personal trainer.

Experienced esthetician and owner of Dermaspace, Jody Leon, is Washington State’s only certified Iderm Facial Treatment specialist, so when you’re with him, your skin is in good hands. He begins the treatment’s four-step process by assessing each client’s skin type. Next comes the detoxification preparation, which he accompanies with a relaxing arm and hand massage – working out never felt so good! After a thorough deep cleaning, Jody ends the treatment with a procedure called ionization, which firms the skin, shrinks pores and decreases inflammation, among other things. Just think of it as the equivalent of a post-workout cool down.

With obvious results and no heavy lifting required, the “Skin-Gym” is the kind of workout everyone dreams of, and at only $85 ($50 for first time clients), this is the kind of deal you can’t refuse.

Courtesy of Local Twist

Saturday, August 14, 2010

Foods, Drugs and Vitamins May Help Prevent Skin Cancer - via Skin Inc.

In most cases, non-melanoma skin cancers are caused by overexposure to ultraviolet radiation, the invisible rays from the sun that can burn the skin. To reduce the risk of skin cancer, dermatologists encourage the public to be sun smart, including limiting sun exposure and using broad-spectrum sunscreens. Despite these efforts, the incidence of non-melanoma skin cancer continues to rise. Now, several agents—including medicines, foods and vitamins—are being investigated for their chemopreventive properties, or ability to prevent skin cancer.

At the American Academy of Dermatology’s Summer Academy Meeting 2010 in Chicago, dermatologist Craig A. Elmets, MD, FAAD, professor and chair, department of dermatology and director of the Skin Diseases Research Center, University of Alabama at Birmingham, discussed promising new research on the use of medicine and diet to prevent UV-induced skin cancer in the future.

“Based on the research conducted thus far, it appears that several different agents have the potential to be effective in providing enhanced sun protection and preventing non-melanoma skin cancers,” said Elmets. “While the way these agents work are different, we have seen encouraging results with both oral and topical agents, including non-steroidal anti-inflammatory drugs (NSAIDs), eflornithine and certain natural antioxidants.”

Medications investigated as future chemopreventive agents

NSAIDs are a class of drugs that block cyclooxygenase enzymes (COX-1 and COX-2), which produce prostaglandins that promote inflammation, pain and fever. When these enzyme messengers responsible for reducing prostaglandins throughout the body are blocked, ongoing inflammation, pain and fever are reduced. One such NSAID approved by the Food & Drug Administration (FDA) and used primarily to treat inflammation associated with arthritis is celecoxib. Elmets noted the chemopreventive agent's use in patients with a syndrome known as basal cell nevus syndrome. Caused by a genetic defect, basal cell nevus syndrome triggers patients to develop basal cell carcinomas at a very young age.

“In patients with basal cell cacinomas, investigators have found that the COX-2 enzyme is elevated in non-melanoma skin cancers. Because celecoxib inhibits this enzyme, clinical studies have demonstrated that taking celecoxib seems to decrease the number of new basal cell carcinomas in basal cell nevus syndrome,” he said. “This is very encouraging, particularly if this can eventually be applied to basal cell skin cancer in the general population.”

According to Elmets, eflornithine is another drug that has been shown to have beneficial effects in preventing basal cell carcinoma. FDA-approved as a topical treatment for excessive hair growth and as an injectable formulation to treat sleeping sickness, eflornithine inhibits the enzyme known as ornithine decarboxylase that is found to be elevated in skin cancers.

“Although celecoxib and eflornithine work by different mechanisms, initial studies show that they both prevent basal cell carcinomas by at least 30%,” said Elmets. “Based on these initial findings, these two drugs are considered very promising as chemopreventive agents and require additional clinical study.”

Natural antioxidants in preventing skin cancer

In addition, numerous natural antioxidants are being evaluated for their chemopreventive properties. Antioxidants are substances that destroy free radicals, which are harmful compounds in the body that damage DNA and even cause cell death. Free radicals are believed to contribute to aging as well as the development of a number of health problems, including skin cancer.

Animal studies and emerging clinical studies suggest that the abundance of antioxidant polyphenols in green tea and grape seed extract may play an important role in helping to prevent the onset and growth of skin tumors. Similarly, the pomegranate fruit also is thought to be effective in promoting skin health since it has very high levels of antioxidants called flavonoids that have been shown to counteract various cancer-causing free radicals.

“It remains unclear precisely how these natural antioxidants work, but they all are considered powerful when used externally,” said Elmets. “These substances also have an anti-inflammatory effect, which is known to be chemopreventive. However, it is important to remember that the FDA has not approved the use of these natural antioxidants as chemopreventive agents, and controlled studies need to be conducted in humans to determine whether they may help prevent skin cancer. At present, the evidence to support these benefits is largely based on animal studies.”

“As dermatologists, we will always recommend sunscreens and sun-smart behaviors, like seeking shade, wearing hats and limiting sun exposure. These lifestyle strategies are vital to preventing skin cancer and should not be replaced,” added Elmets. “However, I could envision in the future that we also may recommend a cocktail of chemopreventive agents to provide patients enhanced protection against UV-induced skin cancers. Our hope is that further human studies will help us better understand how to effectively incorporate these new agents into practice and thereby turn the tide on the escalating rate of skin cancer in this country.”

Find this article at:
http://www.skininc.com/skinscience/physiology/100527674.html

Tuesday, July 20, 2010

Summer Special

Dermaspace is offering a great special for 1st time clients.

$50 for the Iderm Facial Treatment - regular price, $85.

For more information or to book online visit DERMASPACE!

Tuesday, June 22, 2010

Vitamin D Health: Why You Shouldn't Shun the Sun by Dr. Frank Lipman for The Huffington Post

For the last 30 years or so, doctors (dermatologists in particular), health officials, beauty experts and many product companies have been demonizing the sun. They've told us to avoid it because without sunscreen, exposure to the sun's rays will damage skin and cause cancer. But this oversimplification distorts the facts. In the past few years, numerous studies have shown that optimizing your vitamin D levels may actually help prevent as many as 16 different types of cancer including pancreatic, lung, breast, ovarian, prostate and colon cancers. And the best way to optimize Vitamin D levels is through safe, smart and limited sunscreen-free exposure to the sun.

For hundreds of thousands of years, man has lived with the sun: Our ancestors were outdoors far more often than indoors. We developed a dependence on sunshine for health and life, so the idea that sunlight is dangerous does not make sense. How could we have evolved and survived as a species, if we were that vulnerable to something humans have been constantly exposed to for their entire existence? Is it possible that our bodies are made in such a way that the sun is really a lethal enemy? Not in my opinion. Like all living things, we need sunshine, and it feels good for a reason. Much as plants harness the sun's rays through photosynthesis, our bodies use sunlight to help the skin produce the vitamin D it needs to build bones, quell inflammation, bolster the immune system and protect against cancer (including skin cancer).

Why demonize the sun?


Western medicine has made a practice of telling us to abstain from things that are bad for us in extreme quantities, when in fact those same things⎯fat, salt and sunshine for example⎯are very good for us when consumed wisely and in moderation. In the case of sunshine, our UV paranoia is contributing to a silent epidemic: Vitamin D deficiency. It's silent because most people don't know they are deficient. And it's deadly, because this deficiency can lead to cancer and a multitude of other diseases. But we've been brainwashed into believing that even small amounts of sunshine will harm us, and told to slather on sunscreen, which blocks vitamin D production and exacerbates the Vitamin D deficiency induced by our modern, indoor lives.

Studies show that as many as three out of four Americans suffer from Vitamin D deficiency. A study published in 2009 in the Archives of Internal Medicine (a leading scientific journal), found that 70 percent of Caucasians, 90 percent of Hispanics and 97 percent of African Americans in the US have insufficient blood levels of vitamin D. Indeed, it's thought to be the most common medical condition in the world, affecting over one billion people and we now have research showing just how essential vitamin D is to health.

U.S. and Norwegian researchers have found that people who live in higher latitudes are more prone to vitamin D deficiency and more prone to developing common cancers and dying of them. It's now thought that this is due in part to the body's inability to make enough activated vitamin D to help regulate cell growth and to keep cell growth in check. Independent scientific research has shown that whether you live in a sunny or not-so-sunny climate, exposure to the sun and its UVB radiation will increase your production of vitamin D and help lower the risk of a host of debilitating and fatal diseases -- including many cancers, heart disease, high blood pressure, Type I diabetes, multiple sclerosis and depression.

And now the experts are concerned that we're passing an epidemic of vitamin D deficiency down to a new generation. Studies have shown that vitamin D deficiency may imprint on an infant for the rest of his/her life. Infants that are vitamin D deficient at birth can remain vitamin D deficient for the first several months after birth, which may put them at risk of developing many chronic diseases much later in life.

What is Vitamin D and how much do you need?


Although called a vitamin, it is not. Vitamin D is in a class by itself, behaving more like a hormone. It is made in the skin, gets into your bloodstream and then goes into the liver and the kidney where it becomes activated as a key steroid hormone called Calcitriol. It then goes to the intestines, bones and other tissues, effecting metabolic pathways and the expression of myriad genes. Vitamin D's active form can interact with almost every cell in the body directly or indirectly, targeting up to two thousand genes, or about six percent of the human genome. It is necessary for numerous cellular functions, and when the body does not have what it needs to function optimally, it follows that we experience a decline in health and put ourselves at risk of disease. We now know that almost every cell and tissue in our body has vitamin D receptors, which raises the question: Why would those receptors be there if they weren't meant to have an effect?

Our vitamin D needs vary with age, body weight, percent of body fat, latitude, skin coloration, season of the year, use of sun block, individual reactions to sun exposure, and our overall health. As a general rule, older people need more vitamin D than younger people, large people need more that small people, fat people need more than skinny people, northern people need more than southern people, dark-skinned people need more than fair skinned people, winter people need more than summer people, sun-phobes need more than sun worshipers, and ill people may need more than well people.

The best way to determine whether or not you are deficient is to have your vitamin D blood levels measured and replenish accordingly.


My Top 10 Tips for Healthy Sun Exposure and Optimizing your Vitamin D Levels


  • Have a healthy respect for the sun. It is powerful medicine with potentially dangerous side effects on your skin. Treat it like medication, using the lowest dose necessary, but don't avoid it completely. Never fall asleep in the sun without protection.
  • Always avoid sunburn. It is sunburn, not healthy sun exposure that causes problems. Repeated sunburns, especially in children and very fair-skinned people, have been linked to melanoma. Whereas there is no credible scientific evidence that regular, moderate sun exposure causes melanoma or other skin cancers.
  • Prepare your skin and build up tolerance gradually. Start early in the year (spring), or early in the morning before the sun is strongest and slowly build up the amount of time you spend in the sun.
  • Get 15-30 minutes of unprotected sun exposure two to four times a week. Each of us has different needs for unprotected sun exposure to maintain adequate levels of Vitamin D. Depending on your age, what type of skin you have, where you live and what time of the day and year it is, your need will vary. The farther you live from the equator, the more exposure to the sun you need in order to generate vitamin D. For instance, a fair skinned person, sitting on a New York beach in June, in the middle of the day, for about 10-15 minutes (enough to cause a light pinkness 24 hours after), is producing the equivalent of 15,000-20,000 IU's of Vitamin D. But the same person living further north in the U.K, or Canada would need 20-30 minutes to get that light pinkness, which is all one needs. Also, people with dark skin pigmentation may need 20 - 30 times as much exposure to sunlight as fair-skinned people, to generate the same amount of vitamin D. For more specifics, I recommend the tables in The Vitamin D Solution by Dr. Michael Holick.
  • Get frequent, short exposures. Regular short exposures have been found to be much more effective and safer than intermittent long ones. Note that you cannot generate Vitamin D when sitting behind a glass window, because the UVB rays necessary for vitamin D production are absorbed by glass.
  • After your 15-30 minutes of sun-block free time in the sun, you must protect yourself. If you're going to be out in the sun for longer periods, wear a hat to protect your face and light colored clothing that blocks the sun and keeps you cool. When you do apply sunscreen, use one with fewer chemicals. Check out the Environmental Working Group's list of safer sunscreens. Remember that even weak sunscreens block the ability of your skin to manufacture vitamin D, so once you have applied it, you will not be making vitamin D.
  • Boost your "internal sunscreen" by consuming anti-oxidants and beneficial fats. These strengthen skin cells, helping to protect them from sun damage. Eating lots of vegetables and fruits such as blueberries, raspberries, goji berries and pomegranates and supplementing with green powdered mixes and fish oils are great options when going into the sun.
  • Have your vitamin D blood levels checked regularly. The correct blood test is 25OH vit D or 25 hydroxy vitamin D test. Be aware, however, that current "normal" range for vitamin D is 20 to 55 ng/ml. This is much too low! Those levels may be fine if you want to prevent rickets or osteomalacia, but they are not adequate for optimal health. The ideal range for optimal health is 50-80 ng/ml.
  • Don't rely on food alone for your vitamin D needs. It is almost impossible to get your vitamin D needs met by food alone. Fatty wild fish (not farmed), like salmon and mackerel are the best food sources, but you would have to eat huge quantities of them daily to get anywhere near what your body needs. Although fortified milk and orange juice do contain vitamin D, you would have to drink at least 10 glasses of each daily and I don't recommend doing that.
  • Take Vitamin D3 supplements if necessary. In the winter or if you don't get enough healthy sun exposure or if your blood levels are low, make sure you supplement with at least 2,000 IU's a day of Vitamin D3. Although I recommend moderate sunbathing, vitamin D supplements provide the same benefits as sunshine (in terms of Vitamin D needs). But, if taken in too large a dose, they can cause vitamin D toxicity, whereas sun exposure does not. It is impossible to generate too much vitamin D in your body from the sun: Your body will self-regulate and only generate what it needs, which just reaffirms to me that we should get our vitamin D from sensible sun exposure. Here are specific guidelines for replenishing Vitamin D.

Conclusion


Although irresponsible sunbathing is unquestionably harmful and precautions need to be taken, regular, moderate, unprotected sun exposure is essential for good health. It is free, easy to get and good for you when used intelligently. It is the only reliable way to generate vitamin D in your own body, which we now know to be an essential ingredient for optimizing health and preventing disease.

Frank Lipman MD is the creator of Eleven Eleven Wellness, Guided Health Solutions, a leading edge integrative health program.

He is also the founder and director of the Eleven Eleven Wellness Center in NYC, where he practices a combination of Western and Eastern Medicine and the many other complimentary modalities he has studied. He is the author of the recent REVIVE; Stop Feeling Spent and Start Living Again (2009) (previously called SPENT) and TOTAL RENEWAL; 7 key steps to Resilience, Vitality and Long-Term Health (2003).

Follow Dr. Frank Lipman on Twitter: www.twitter.com/lipmo

Thursday, June 3, 2010

"Stem Cell Science & Age Management of Skin" By: Christine Heathman for Skin Inc.


Editor’s Note: This article is based on a presentation that will be presented by the author at Face & Body Northern California, July 17–19, 2010, at the San Jose McEnery Convention Center in San Jose, California. To learn more about and register for this event, log on towww.FaceandBody.com/california.

“The development of cell lines that may produce almost every tissue of the human body is an unprecedented scientific breakthrough. It is not too unrealistic to say that this research has the potential to revolutionize the practice of medicine, and improve the quality and length of life.”

—Harold Varmus, Nobel Prize winner and former director, National Institutes of Health

Fighting the skin-aging clock now requires more understanding of ingredient science and the anatomy, histology and physiology of the skin. Research in skin biology began charting an interdisciplinary approach to the skin sciences several decades ago, but the demand for anti-aging ingredients has driven the need for the progressive age management of skin to an all-time high. A recent study conducted by an independent survey reports more than 62% of women between the ages of 35–54, and more than 65% of women 55 and older, affirm that aging is their reason for using skin care products.1

It is unavoidable: Skin ages. The genetic answer to skin aging lies in the fact that each gene codes for a specific protein, and proteins determine how cells work. Proteins, such as collagen, provide bodily structure by connecting tissues and organs. In the case of skin, collagen acts as scaffolding holding up the skin, and keeping it smooth and wrinkle-free. Wrinkles are the benchmark of declining collagen levels and can affect all age groups when UV radiation assaults cells, breaking down DNA via the sun’s proton energy.

The innate aging process is made worse via UV radiation, chemical compositions of tissue change, sun, pollution, heat, smoking, drugs, stress, diet and other environmental factors affecting the challenge of skin aging. Because of this, new revolutionary ingredients that combat chronological aging, reduce superficial and deep wrinkles, delay senescence of essential cells, and preserve the youthful appearance and vitality of skin have been discovered using the biotechnology of plant stem cell extracts. Plant stem cell extracts have been proven to protect skin from UV oxidative stress and inhibit inflammation; control UV-induced matrix metalloproteinase (MMP) activation, collagen loss and tissue damage; and combat destructive free radical injury that leads to photoaging.2

What are stem cells?

Stem cells are unprogrammed cells that can differentiate into a cell with specific functions. They are related to longevity and have a unique growth characteristic allowing them to make identical copies of themselves, as well as differentiate to become specialized cells. Stem cells have the capacity to replenish themselves through self-renewal, and the ability to generate differentiated cells. Each cell, whether stem cell or differentiated cell, has the same DNA—or genes—but a stem cell’s characteristic depends on signals from the microenvironment, such as neighboring cells that form a function. Principally, there are signals inside each cell that control its fate called epigenetic signals. They are tags on the DNA or surrounding histone proteins regulating the switching on or off of genes.

The most remarkable feature of cells is their ability to reproduce. Any cell is simply a compartment with a watery interior separated from the external environment by a surface membrane, which can be thought of as a plasma film, preventing the free flow of molecules in and out of the cell. The simplest type of reproduction entails the division of a parent cell into two daughter cells. This occurs as part of the cell cycle, a series of events that prepares a cell to divide followed by the actual division process, called mitosis.

In single-cell organisms, both daughter cells often resemble the parent cell. In multicellular organisms, stem cells can give rise to two different cells: one that resembles the parent cell and one that does not.

Stem cells and skin

High-tech plant cell cultures have been harnessed to protect skin stem cells based on the science of botanical wound-healing. To understand how these ingredients function, it is important to understand the relationship of the stem cell population with other cells of the skin.

The skin. The skin is the largest and most dynamic immune organ, made up of billions of cells playing a protective and esthetic role where aging is clinically evident via wrinkles. Two types of adult stem cells have been identified within the skin’s ecosystem: epithelial skin cells located in the basal layer of the epidermis, and hair bulge stem cells situated in the hair follicle.

The skin’s top layer, the epidermis, is a stratified epithelium housing terminally differentiated cells that shed by the millions daily from the skin, continuously delivering new skin cells. Because of this differentiating cell dynamic, the importance of stem cells in the skin is scientifically substantiated, enumerating their relevance to skin age management.

The role of the epidermis stems directly from the terminal differentiation of keratinocytes into corneocytes to form what is the visible skin. This dynamic and complicated immune organ interfaces with a hostile environment, and its uppermost layer, the stratum corneum, is subject to continuous abrasion by chemical and physical injury. The stratum corneum, an essential part of the epidermis, is the outermost skin layer at the environment interface. This skin layer is also the principal permeability barrier to transepidermal water loss (TEWL) and a major cordon to percutaneous absorption of topically applied compounds, such as botanical stem cell extracts. The degree of moisture in the stratum corneum is an important factor when evaluating skin function because loss of moisture is a major factor in aging skin. This detail is important to note when treating and managing photoaging skin because there is a significant correlation between TEWL and the percutaneous absorption of topical ingredients.

Why is TEWL an important measurement in aging skin? Water in the stratum corneum is a dynamic equilibrium between the underlying tissues and the environmental atmosphere. The intricate stratum corneum barrier constitutes 70% of the epidermis, which is continuously rehabilitated from the granular layer. This layer is the first victim of UV assault that eventually results in photoaging of the skin. To protect the epidermis against invasion of microorganisms and toxic agents, as well as the loss of indigenous fluids residing in the stratum corneum, the horny layer of the skin must be perpetually renewed. This is where stem cells play an important role.

Stem cells’ role in the skin. The stem cell, which is responsible for cell renewal replacement in the epidermis, is an intermediate between the keratinocyte stem cell and terminally differentiating cells. The stem cell is the amplifying cell that undergoes limited cycles of replication. One of the key questions in stem cell research has been how stem cells know when it’s time to stop reproducing. In some cases, stem cells seem to be able to divide into two structurally different cells; one that remains a stem cell and another, called a progenitor cell, that goes on to generate specialized cells. Details still remain unclear, so this area of research remains active, however the study with skin stem cells reveals important information about other organs of the body.

Researchers believe certain proteins and other signaling or controlling molecules are responsible for directing cell specialization, however they are still actively working to identify the specific molecules that control normal skin development. Scientists recognize skin stem cells are the decision-makers that direct the production of new skin cells, as is evidenced by the daily shedding of dead stratum corneum epithelium.3 If skin stem cells did not preside over and create skin cell replacements, they certainly would suffer a fateful demise.

Skin stem cells generate new skin to replace the cells lost every day and influence wound-healing. Skin begins with a single cell. One cell, dividing into two, then two into four and four into eight until there are billions of cells, patterned and diffuse, color-coded and clear, working-class and upper crust, ancient and young, defenders and helpers, assembled into a great, thriving mass that is a complete skin organ. And from this, millions drop from the skin daily and the replication process keeps new generations of cells in a replenishment course of action that can repeat itself more than 900 times during a life cycle of self-renewal.

Cell lineage. The formation of working tissues during the development of multicellular organisms depends in part on specific patterns of mitotic cell division. A series of such cell divisions similar to a family tree is called cell lineage, which traces the progressive determination of cells, restricting their developmental potential and their differentiation into specialized cell types. Cell lineages are controlled by intrinsic factors—cells acting according to their history and internal regulators—as well as extrinsic factors such as cell-cell signals and environmental inputs.

A cell lineage begins with stem cells. The stem cell name comes from the image of a plant stem, which grows upward, continuing to form more stems, while sending off leaves and branches to the side. The stem cell is as important to a differentiating skin cell as a branch is to a leaf. Healthy stem cells mean healthier, younger-acting skin.

Stem cells and age management

With current applications for treating and managing aging skin, scientists are focusing their research on adult stem cells located in the skin and are studying the potential of this cell type, coupled with its function related to chronological aging to help understand how the skin’s aging clock can be reset.2 Epidermal adult stem cells replenish and maintain the balance of cells within the skin tissue, and regenerate tissue caused by damage from a variety of sources, such as the sun, injury and acne. Age is the major adversary, and it diminishes the number of skin stem cells, making their ability to repair the skin less efficient.

Plants have stem cells comparable to human stem cells. Unlike humans, plants contain totipotent stem cells with the potential to regenerate a whole plant. This action gives scientific rise to the benefits of the plant stem cells’ ability to regenerate new leaves, flowers, seeds or a whole, fresh plant. Unlike human stem cells, plant stem cells can de-differentiate and become a stem cell.2

The stem cell ingredient that has garnered much attention lately is the extract called Malus domestica, sourced from a rare Swiss apple identified as the Uttwiler Spatlauber. The Uttwiler Spatlauber apple is an endangered variety that is well-known for its excellent storability and longevity potential due to its long-living tissue stem cells. Fruit is known to oxidize quickly once removed from its primary host and exposed to the environment; however, this is not the case with the Uttwiler Spatlauber apple.2

It is an anomaly among fruit, resisting typical oxidation due to its high tannin content and long-living stem cells. In order to use the stem cells from this apple, scientists had to extract tissue from the plant to create cultures called explants. The explants are then scratched to create miniature wounds to stimulate the stem cells within the cultured plant tissue. This action induced the formation of new stem cells.2

Biotechnologies of plant stem cell extracts also isolate the substances involved in the plant’s defensive ability against environmental, physical and biological stressors. Scientists in Switzerland studied the liquid cell cultures derived from their extensive study of the Uttwiler Spatluber apple and have found that the stem cells extracted from it can stimulate human stem cell growth and protect skin stem cells from death due to UV overexposure, neutralizing free radicals and reversing the effects of photoaging of the skin. Other biotechnological research in botanical stem cell research is emerging quickly in professional skin care to benefit the management of aging skin.2

A revolutionary approach

This is an exciting time to be in specialized skin care as a new approach to age management is becoming available through the use of stem cells. Professional age management of skin is all about extending and preserving the life energy of skin cells to help yield results for younger-acting skin. Current applications for treating aging skin will continue to lead scientists to focus their research on adult stem cells located in the skin, and the continued study of these cells, their function relating to aging and how they helps reset the skin’s aging clock, is groundbreaking and revolutionary.

REFERENCES

1. www.SkinInc.com/treatments/facial/84014002.html (Accessed May 10, 2010)

2. C McKiver, Plant Stem Cells: A Cure for Aging?, Inside Cosmeceuticals (Aug 3, 2009)

3. R Barthel and D Aberdam, Epidermal stem cells, Journal of the European Academy of Dermatology & Venereology 19(4) 405–413 (2005)

Find this article at:
http://www.skininc.com/skinscience/physiology/94947479.html

Copyright © 2008 Allured Publishing. All rights reserved.

Thursday, May 13, 2010

Stress & Skin, brought to you by The American Academy of Dermatology

How the Mind Matters to Your Skin

How we feel on the inside could be affecting how we look on the outside. In fact, studies link factors that impact our emotional well-being — such as stress, depression and anxiety — to an increase in skin, hair or nail problems. Dermatologist and clinical psychologist Richard G. Fried, MD, PhD, FAAD, of Yardley, Pa., explains the reciprocal relationship between feelings and appearance:

Psychodermatology Interventions

        • Stress can manifest itself on one's appearance in many ways, but primarily by making the skin more sensitive and more reactive.
          • For example, stress can make psoriasis or rosacea worse, result in acne lesions that are more inflamed and more persistent, cause brittle nails and ridging of the nails, cause hair loss, cause or worsen hives, and cause excessive perspiration.
          • Stress also is a known trigger or can be a worsening factor for fever blisters, psoriasis, seborrheic dermatitis and has even been shown to impair skin barrier function and dehydrate the skin — allowing more irritants, allergens, and infectious agents to penetrate the skin and cause problems.
        • Beyond the direct physiological effects of stress, patients under stress also tend to neglect or abuse their skin. For example, they often lack the energy and motivation to adhere to their skin care regimens, and there also might be signs of stress-related behaviors — such as scratching, pulling or rubbing — that can exacerbate problems.
        • Traditional dermatologic therapies should be used in conjunction with appropriate stress management therapies to successfully treat stress-related dermatologic conditions.
          • When dermatologists treat both the skin and stress, the skin often clears more quickly and completely as the influences of stress are diminished. This, in turn, can help decrease a patient's overall anxiety level, and the patient may start to feel better about how they look and how they feel emotionally.
        • On a microscopic level, stress reduction can decrease the release of pro-inflammatory stress hormones and chemicals. For example, release of neuropeptides (or stress chemicals released from the nerve endings) can be reduced with stress management techniques. This often results in skin that looks and functions better.
          • These interventions can reduce blood vessel over-activity, resulting in less blushing or flushing.
        • With accurate diagnosis by a dermatologist, effective treatments improve the appearance and function of the skin. This alone can substantially reduce patients' stress and improve their skin, hair and nail conditions. However, if stress is clearly interfering with patients' overall well-being and ability to cope, simultaneous stress management interventions are warranted. In some instances, referral to a mental health professional may be necessary.

Cosmetic Interventions

    • While skin rejuvenation procedures have been shown to significantly improve a person's outward appearance, studies suggest these types of cosmetic interventions also can have positive effects on how people feel and how they function.
      • When people feel more attractive and more confident in their appearance, they tend to perform better in other areas of their lives — in their work, family life, social life, and marriage or personal relationships.
      • Under the right circumstances, cosmetic procedures can be a powerful ally, but it's important for patients to understand that these procedures are not a panacea.
    • In a 2008 study designed to measure the positive ripple effects of botulinum toxin injections on other aspects of patients' lives, Dr. Fried found that patients treated with botulinum toxin clearly experienced substantial benefits. His key findings include:
      • 29 percent reported feeling less anxious
      • 36 percent said they feel more relaxed
      • 49 percent were more optimistic
    • A previous study conducted by Dr. Fried evaluating the clinical and psychological effects of the use of alpha hydroxy acids (AHAs) found that patients demonstrated significant improvements in facial skin tone and fine wrinkling, and reported satisfaction with their physical appearance and the quality of their interpersonal relationships.

For more information on the effects of stress on skin, hair and nails, visit the American Academy of Dermatology's website at www.aad.org.

November 2008

Thursday, May 6, 2010

What is used in the Iderm Treatment?

The Iderm Treatment


To prep the skin I start with a process called a Moisture Pack where I place pieces of fabric that have been soaked in Dermaculture’s Yucca Solution. This solution is derived from the Yucca plants of the southwestern desert, and is an excellent facial cleanser and is also anti-inflammatory. After placing the fabric on the face I then cover the face with an infrared heat dome or "dry heat" for about 10 minutes.

Yucca is high in vitamins A, B and C and contains potassium, calcium, phosphorus, iron, manganese and copper which make it very soothing to the skin, bones and muscles.
The ingredients are over 95% Yucca with stabilizers.

This treatment helps to cleanse the walls of the pores, making it ideal in preparing the skin for extractions.



After extractions I then wrap the skin with cotton and fabric that has been soaking in Dermaculture’s Positive Solution.


This is used to treat acne, age spots, rosacea and psoriasis. This will also give a more youthful glow to the skin, and is beneficial to all skin types.

The Positive Solution is made from a perfect balance of zinc sulfate (Zinc sulfate is used to destroy harmful micro-organisms on the skin and also for its astringent action), citric acid (Vitamin C) and epson salts. The ingredients are very rich in vitamins and minerals. These ingredients work together to increase oxygen, hydration and circulation. The solution is antibacterial and aids in detoxification. It promotes healing, stimulates skin renewal and collagen growth.

The Iderm Treatment is highly recommended before surgical procedures to help prepare the skin for surgery and after surgery to help with the healing process and to prevent scarring.

For more information about this awesome skin treatment visit my website at www.dermaspace.com.